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Pouchology.org

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IPAA / Pouch Literature Collection
A curated collection of peer-reviewed literature on the ileal pouch-anal anastomosis (IPAA) and continent ileostomy (Kock pouch) — restorative surgical alternatives to permanent ileostomy for ulcerative colitis and familial polyposis.
Searches title, author, abstract, and snippet — full-text search coming soon.
Ask PouchRAG Coming Soon

What is Pouchology?

Pouchology is an AI-curated collection and searchable knowledge base of 7,228 peer-reviewed publications on the ileal pouch-anal anastomosis (IPAA, or "J-pouch") and continent ileostomy (Kock pouch), including 1,014 with full-text extractions. It covers the full scope of pouch surgery: operative technique, complications, quality of life, long-term outcomes, pouchitis, fertility, revisional surgery, and emerging topics like biologics and robotic approaches.

This collection spans nearly 61 years (1965–2026) with 100% PubMed identifier coverage. Papers are indexed by first author, year, PMID, and searchable abstract and full text. This is a research tool — enter any clinical question above to find relevant evidence.

19902000201020207,228
Complications
2,232 studies
Pouchitis
1,765 studies
Crohn's of the Pouch
935 studies
FAP
838 studies
Quality of Life
750 studies
Pouch Survival
689 studies
Anastomotic Leak
593 studies
Fistula
564 studies
Obstruction
469 studies
Incontinence
458 studies
Pouch Excision
432 studies
Dysplasia & Cancer
383 studies
Continent Ileostomy
350 studies
Stricture
347 studies
Biologics
276 studies
Mucosectomy
243 studies
Sexual Function
239 studies
Pelvic Sepsis
223 studies
Robotic Surgery
203 studies
Meta-Analysis
136 studies
MIS / Robotic
101 studies
Fertility & Pregnancy
100 studies
Irritable Pouch
90 studies
Microbiome
90 studies
Cuffitis
82 studies
Afferent Limb
81 studies
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PouchRAG — AI-Powered Q&A

Ask clinical questions in plain language and get evidence-based answers synthesized from over 900 IPAA publications, with cited sources.

Coming Soon

PouchRAG uses retrieval-augmented generation (RAG) — an AI technique that searches the literature collection first, then generates an answer grounded in the actual studies it finds, rather than relying on general knowledge alone.

In the meantime, use Search Collection to find papers by keyword.

Contact

Interested in collaborating, learning more about Pouchology, or have a question? We'd love to hear from you.

We typically respond within a few business days.

Why Pouchology?

Ileal pouch–anal anastomosis (IPAA) and continent ileostomy (Kock pouch) are among the most complex reconstructive procedures in gastrointestinal surgery. The published literature on pouch surgery spans over five decades, thousands of papers, and dozens of subspecialty topics—from pouchitis and fistula management to fertility, robotic technique, and long-term quality of life.

Yet this knowledge is scattered across journals, hard to search, and often inaccessible to the clinicians and patients who need it most.

Pouchology was created to solve this problem. It is an AI-curated collection and searchable knowledge base of over 7,200 peer-reviewed publications on the ileal pouch and continent ileostomy, including 1,014 with full-text extractions. Every paper is indexed by topic, author, year, and PMID, classified by study type, and searchable across abstracts and full text.

The topic summaries and evidence overviews you see on this site were generated by artificial intelligence to help users quickly orient to each area of pouch literature. They are not a substitute for reading the primary sources—they are a starting point.

Pouchology is a project of the iPouch Consortium, an international quality improvement initiative dedicated to advancing the care of pouch patients worldwide.

About the Founder

Stefan D. Holubar, MD, MS — Professor of Surgery, Cleveland Clinic — Founder, Pouchology.org

Stefan D. Holubar, MD, MS, FACS, FASCRS

Professor of Surgery • Case Western Reserve University and Cleveland Clinic Lerner College of Medicine

Stefan Holubar brings a unique perspective to pouch surgery: he is both a fellowship-trained colorectal surgeon specializing in ileal pouch procedures and himself a pouch patient. This dual lived experience—from both sides of the operating table—drives his commitment to ensuring that every patient who needs a pouch receives the highest quality of care.

Dr. Holubar is co-PI of the Crohn's & Colitis Foundation IBD-SIRCQ, co-PI of the ACS-NSQIP IBD Collaborative (26 sites nationally), founder of the iPouch Consortium, and has authored over 300 peer-reviewed publications, the majority focused on IBD surgical outcomes.

Co-Investigator

Kevin Chen, MD — Multimodal AI Expert, Cleveland Clinic — Co-Investigator, Pouchology.org

Kevin Chen, MD

Multimodal AI Expert • Cleveland Clinic

Kevin Chen is a multimodal AI expert and Co-Investigator on Pouchology.org, bringing expertise in retrieval-augmented generation, natural language processing, and clinical decision support systems to the development of PouchRAG.