Wiki · Pouchology
36 questions, drawn from this site's literature corpus. Draft pages are not yet clinician-reviewed.
Does preoperative anti‑TNF exposure increase the risk of postoperative anastomotic leak compared with preoperative integrin antagonists such as vedolizumab draftIn chronic antibiotic‑refractory pouchitis after multiple failed courses of oral antibiotics, is anti‑TNF or fecal microbiota transplantation preferred draftIn patients with chronic antibiotic‑refractory pouchitis and mild EIM, is systemic corticosteroid therapy or azathioprine preferred as first‑line immunosuppression draftWhat is the evidence that anti‑TNF is superior to vedolizumab for inducing remission in chronic antibiotic‑refractory pouchitis draftIn patients with de novo CD of the pouch, does infliximab provide superior remission rates compared with adalimumab draftIn recurrent cuffitis despite adequate topical therapy, is adding azathioprine or surgical revision of the rectal cuff preferred draftWhat is the evidence for fecal microbiota transplantation in refractory cuffitis draftWhat is the evidence that aspirin reduces the risk of malignant transformation in pouch adenomas in patients with FAP draftWhat is the evidence that early IPAA before rectal polyps develop reduces long‑term CRC risk in patients with FAP compared with delayed surgery after polyp burden increases draftDoes laparoscopic IPAA lead to fewer postoperative complications than open IPAA in patients with UC draftWhat is the evidence that intentional IPAA in patients with CD and active rectal inflammation yields acceptable long‑term pouch outcomes draftWhat are the most common risk factors for portomesenteric venous thrombosis after colorectal resection draftWhat is the evidence that early therapeutic anticoagulation improves survival in patients with portomesenteric venous thrombosis compared with delayed treatment draftDoes IRA result in lower postoperative fecal incontinence scores compared with end ileostomy in patients with UC draftIn women desiring future pregnancy after IPAA, is a W pouch or J pouch preferred for obstetric outcomes draftWhat are the typical diagnostic criteria for evacuation dysfunction in patients with IPAA draftIs high‑resolution anorectal manometry superior to standard manometry for diagnosing dyssynergia in irritable pouch patients draftWhat is the evidence that pelvic floor rehabilitation improves quality of life in patients with evacuation dysfunction after IPAA draftIn patients with UC and chronic pouchitis refractory to maximal medical therapy, is pouch excision with permanent ileostomy or continued aggressive medical management preferred draftDoes hand‑sewn ileoanal anastomosis result in higher rates of pouch failure compared with stapled anastomosis in patients with UC draftIn patients with early postoperative pouch inflammation and a smoking history, does prophylactic immunomodulator therapy reduce the risk of pouch failure draftWhat is the rate of infertility in women after IPAA for UC draftIn complex perianal fistula involving an ileal pouch, is seton drainage followed by definitive repair or immediate definitive repair without prior drainage preferred draftWhat is the typical range of daily stool frequency in patients with IPAA at 5 years postoperatively draftWhat is the typical time interval from IPAA to development of a pouch inlet stricture draftWhat is the evidence that early surgical intervention reduces recurrence rates compared with repeated endoscopic dilatations in patients with refractory pouch inlet strictures draftIn patients with UC refractory to medical therapy, is IPAA or permanent ileostomy preferred based on long‑term pouch survival data draftWhat is the evidence that annual pouchoscopy after IPAA reduces overall mortality from pouch cancer compared with surveillance every 3 years draftIn symptomatic floppy pouch with recurrent abdominal pain, is endoscopic balloon dilation or laparoscopic pouch revision preferred draftWhat is the evidence that endoscopic mucosal resection improves outcomes in patients with pouch prolapse draftWhat is the definition of mesenteric lengthening in colorectal surgery draftIn redo IPAA, does hand‑sewn anastomosis result in lower postoperative leak rates compared with stapled anastomosis draftIs chromoendoscopy superior to high‑definition white‑light endoscopy for detecting dysplasia in ileal pouches during surveillance draftIn recurrent pouchitis after two courses of antibiotics, is a short course of oral corticosteroids or biologic therapy such as vedolizumab preferred draftWhat are the limitations of the evidence comparing vedolizumab versus ustekinumab for maintenance therapy in refractory pouchitis draftIn acute severe colitis, does laparoscopic subtotal colectomy result in lower postoperative complication rates than open subtotal colectomy draft